Ítem
Solo Metadatos
Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria
dc.creator | Cubillos, Marcia | spa |
dc.creator | Alba, Martha Patricia | spa |
dc.creator | Bermudez, Adriana | |
dc.creator | Trujillo, Mary | spa |
dc.creator | Patarroyo, Manuel Elkin | spa |
dc.date.accessioned | 2020-08-19T14:40:09Z | |
dc.date.available | 2020-08-19T14:40:09Z | |
dc.date.created | 2003-07 | spa |
dc.description.abstract | Three Plasmodium falciparum serine repeat antigen (SERA) protein peptides were studied by NMR and structure calculations being done in 70:30 water:trifluoroethanol solution. Peptide 22834 was shown to be immunogenic and protective against malaria in Aotus monkeys, whilst native peptide 6737 and its analogue 14096 did not present protection against the disease in these monkeys. Results showed a relationship between these peptides’ secondary structure and their function as immunogen against malaria. | eng |
dc.format.mimetype | application/pdf | |
dc.identifier.doi | https://doi.org/10.1016/S0300-9084(03)00136-6 | |
dc.identifier.issn | ISSN: 0300-9084 | |
dc.identifier.issn | EISSN: 1638-6183 | |
dc.identifier.uri | https://repository.urosario.edu.co/handle/10336/26739 | |
dc.language.iso | eng | spa |
dc.publisher | Société Française de Biochimie et Biologie Moléculaire (SFBBM) | spa |
dc.publisher | Elsevier | spa |
dc.relation.citationEndPage | 657 | |
dc.relation.citationIssue | No. 7 | |
dc.relation.citationStartPage | 651 | |
dc.relation.citationTitle | Biochimie | |
dc.relation.citationVolume | Vol. 85 | |
dc.relation.ispartof | Biochimie, ISSN: 0300-9084;EISSN: 1638-6183, Vol.85, No.7 (2003); pp. 651-657 | spa |
dc.relation.uri | https://www.sciencedirect.com/science/article/abs/pii/S0300908403001366 | spa |
dc.rights.accesRights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.acceso | Restringido (Acceso a grupos específicos) | spa |
dc.source | Biochimie | spa |
dc.source.instname | instname:Universidad del Rosario | |
dc.source.reponame | reponame:Repositorio Institucional EdocUR | |
dc.subject.keyword | Malaria | spa |
dc.subject.keyword | Peptides | spa |
dc.subject.keyword | SERA protein | spa |
dc.subject.keyword | Structure | spa |
dc.subject.keyword | Vaccine | spa |
dc.title | Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria | spa |
dc.title.TranslatedTitle | Los análogos de péptidos de la proteína SERA de Plasmodium falciparum que tienen regiones helicoidales cortas inducen protección contra la malaria | spa |
dc.type | article | eng |
dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | |
dc.type.spa | Artículo | spa |