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Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance

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dc.contributor.advisorOndo Méndez, Alejandro Oyono
dc.creatorMilanés Escobar, Sonia Alejandra
dc.creatorCuadrado Velásquez, Nelia Patricia
dc.creatorDel Valle Zapata, Brenda Milena
dc.creator.degreeEspecialista en Epidemiología (en Convenio con el CES)spa
dc.creator.degreetypeFull timespa
dc.date.accessioned2019-10-07T12:07:32Z
dc.date.available2019-10-07T12:07:32Z
dc.date.created2019-09-06
dc.descriptionAntecedentes: El cáncer es una de las enfermedades crónicas con mayor morbimortalidad a nivel mundial. Se ha incrementado la preferencia de terapias alternativas en pacientes con cáncer como es la Amigdalina, pero se desconoce la extensión y naturaleza de la literatura respecto de ésta. Objetivo: Describir la naturaleza, variedad y extensión de la literatura alrededor del uso de Amigdalina en pacientes con cáncer. Metodología: Revisión sistemática de literatura de alcance. Se consultaron las bases MEDLINE a través de PUBMED, EMBASE, LILACS y literatura gris en google scholar. Se incluyeron estudios en humanos o tejido humano (in vitro) con cualquier tipo de cáncer, toda presentación y vías de administración de la Amigdalina. Tres revisores (SM, NC y BV) independientemente, tamizaron y extrajeron datos. Se sintetizó en: autores, año de publicación, país, tipo de estudio, tamaño de muestra, población y tipo de intervención. Resultados: De 2.402 referencias se removieron duplicados. En el tamizaje de título y resumen se excluyen 399 artículos. De 216 artículos completos se incluyeron 35 en la síntesis. Se reportaron revisiones narrativas (n = 15), estudios experimentales in vitro (n=12), reportes de casos (n=4), revisiones sistemáticas (n=2) y observacionales (n=2). El principal país en publicar fue Estados Unidos, seguido por Alemania. Discusión: No se recuperó toda la evidencia alrededor del uso de Amigdalina. Esto hace mas compleja la interpretación y el análisis de los datos recolectados. Conclusión: No hubo discrepancia entre los autores para no recomendar el uso de Amigdalina como tratamiento para pacientes con cáncer.spa
dc.description.abstractBackground: Cancer is one of the chronic diseases with the highest morbidity and mortality worldwide. The preference of alternative therapies in patients with cancer such as Amygdalin has increased, but the extent and nature of the literature regarding this is unknown. Objective: Describe the nature, variety and extent of the literature surrounding the use of Amygdalin in cancer patients. Methodology: Systematic review of scope literature. The MEDLINE bases were consulted through PUBMED, EMBASE, LILACS and gray literature in google scholar. Studies in human or human tissue (in vitro) with any type of cancer, all presentation and routes of administration of Amygdalin were included. Three reviewers (SM, NC and BV) independently screened and extracted data. It was synthesized in: authors, year of publication, country, type of study, sample size, population and type of intervention. Results: Duplicates were removed from 2,402 references. 399 articles are excluded in title and summary screening. Of 216 full articles, 35 were included in the synthesis. Narrative reviews (n=15), experimental in vitro studies (n=12), case reports (n=4), systematic reviews (n=2) and observational (n=2) were reported. The main country to publish was the United States, followed by Germany. Discussion: All evidence surrounding the use of Amygdalin was not recovered. This makes the interpretation and analysis of the data collected more complex. Conclusion: There was no discrepancy among the authors for not recommending the use of Amygdalin as a treatment for cancer patients.spa
dc.description.embargo2019-10-07 07:15:01: Script de automatizacion de embargos. 7 de octubre El autor selecciona el tipo de acceso restringido, se asigna embargo por dos años. Se ha realizado la publicación de su documento "Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance" en el Repositorio Institucional EdocUR de la Universidad del Rosario. Usted escogió la opción "Restringido (Temporalmente bloqueado)", por lo que el documento ha quedado con embargo hasta el 8 de octubre de 2021, en concordancia con las Políticas de Acceso Abierto de la Universidad. Si usted desea dejarlo con acceso abierto antes de finalizar dicho periodo o si por el contrario desea extender el embargo al finalizar este tiempo, puede enviar un correo a esta misma dirección realizando la solicitud. Tenga en cuenta que los documentos en acceso abierto propician una mayor visibilidad de su producción académica y científica. Se le envía correo 7 de octubre 2019 informando el tiempo de embargo del documento.
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dc.identifier.doihttps://doi.org/10.48713/10336_20396
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/20396
dc.language.isospaspa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de medicinaspa
dc.rightsAtribución-SinDerivadas 2.5 Colombiaspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
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dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectLaetrilespa
dc.subjectAmigdalinaspa
dc.subjectAmigdalosidaspa
dc.subjectNeoplasiaspa
dc.subjectEfectividadspa
dc.subject.ddcCiencias médicas, Medicinaspa
dc.subject.keywordLaetrilespa
dc.subject.keywordAmygdalinspa
dc.subject.keywordAmygdalosidespa
dc.subject.keywordNeoplasmspa
dc.subject.keywordEffectivenessspa
dc.subject.lembMedicinaspa
dc.subject.lembEpidemiologíaspa
dc.titleUso de Amigdalina en pacientes con cáncer: revisión sistemática de alcancespa
dc.typebachelorThesiseng
dc.type.documentRevisión sistemáticaspa
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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