Ítem
Acceso Abierto
Estudio Costo-Efectividad de Lidocaína tópica como adyuvante a Pregabalina y Gabapentina en dolor neuropático periférico en una I.P.S de Bogotá 2011.
| dc.contributor.advisor | Trillos Peña, Carlos Enrique | |
| dc.creator | Cifuentes, Paul | |
| dc.creator | Hinestrosa, Francisco | |
| dc.creator.degree | Especialista en Epidemiología (en Convenio con el CES) | |
| dc.date.accessioned | 2013-06-12T20:45:37Z | |
| dc.date.available | 2013-06-12T20:45:37Z | |
| dc.date.created | 2013-05-14 | |
| dc.date.issued | 2013 | |
| dc.description | Introducción: el dolor neuropático es una patología de considerable prevalencia e impacto socio-económico en la población latinoamericana, la evidencia clínica sugiere que los ligandos de canales de calcio y el parche de Lidocaína pueden tratar exitosamente el dolor neuropático periférico y localizado. Metodología: se realizo una evaluación económica tipo costo-efectividad, observacional y retrospectiva con datos extraídos de las historias clínicas de pacientes atendidos en la clínica de dolor de la IPS. La variable primaria de efectividad fue la mejoría del dolor medida mediante escala visual análoga. Resultados: se estudiaron 94 pacientes tratados con: Gabapentina (G) 21, Pregabalina (P) 24, Gabapentina+ lidocaína (G/P) 24, Pregabalina + Lidocaína (P/L) 25, los costos asociados al tratamiento son los siguientes COP$114.070.835, COP$105.855.920, COP$88.717.481 COP$89.854.712 respectivamente, el número de pacientes con mejoría significativa de dolor fue: 8,10,9 y 21 pacientes respectivamente. El ICER de G/L con respecto a G fue: COP$ -25.353.354. El ICER de P/L con respecto a P fue: COP$ -1.454.655. Conclusiones: la adición del parche de lidocaína a la terapia regular con P/L represento una disminución de consumo de recursos en salud como uso de medicamentos co-analgésicos, analgésicos de rescate y fármacos para controlar reacciones adversas, de la misma forma que consultas a profesionales de la salud. Cada paciente manejado con P/L representa un ahorro de COP $1.454.655 al contrario si se manejase con el anticonvulsivante de manera exclusiva, en el caso de G/L este ahorro es de COP $ 25.353.354 frente a G sola. | spa |
| dc.description.abstract | Abstract: Introduction: Neuropathic pain represents a considerable socio-economic burden with increasing prevalence among the Latin American population; the evidence suggests that calcium channel ligands (Pregabalin, Gabapentin) and the lidocain patch can successfully treat localized neuropathic pain. Methods: We performed an observational, retrospective cost effectiveness economic evaluation with data taken from the clinical records of patients consulting to the pain clinic of the insurer’s institution. The primary effectiveness variable was the Visual Analog Scale (VAS) improvement. Results. We had 94 patients fulfilling our inclusion criteria and were treated with either: Gabapentin (G) 21, Pregabaline (P) 24, Gabapentin + patch (G/L) 24, Pregabaline + patch (P/L) 25, the related costs are as follows respectively: COP$114.070.835, COP$105.855.920, COP$88.717.481 COP$89.854.712. The number of patients with a meaningful improvement in the pain scale (VAS) was: 8,10,9, and 21 respectively. The ICER for G/L compared to G was: COP$-25.353.354. The ICER for P/L compared to P was COP$-1.454.655. Conclusions. The addition of the lidocaine patch to standard therapy with either pregabaline or gabapentin decreased health resources consumption such as drugs used as co-analgesics, rescue analgesics and adverse event treatments, also it decreased the number of physician visits. We can conclude that for every patient treated with G/L the institution can save up to COP$25.353.354 instead of treatment with G alone. Equally patients treated with P/L represented a reduction in the institution’s budget consumption of COP$1.454.655 as compared to P alone. | eng |
| dc.description.sponsorship | Grunenthal | spa |
| dc.format.mimetype | application/pdf | |
| dc.format.tipo | Documento | spa |
| dc.identifier.doi | https://doi.org/10.48713/10336_4440 | |
| dc.identifier.uri | http://repository.urosario.edu.co/handle/10336/4440 | |
| dc.language.iso | spa | |
| dc.publisher | Universidad del Rosario | spa |
| dc.publisher.department | Facultad de medicina | spa |
| dc.rights.accesRights | info:eu-repo/semantics/openAccess | |
| dc.rights.acceso | Abierto (Texto completo) | spa |
| dc.rights.cc | Atribución-NoComercial-SinDerivadas 2.5 Colombia | spa |
| dc.rights.licencia | EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARÁGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | |
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| dc.source.instname | instname:Universidad del Rosario | spa |
| dc.source.reponame | reponame:Repositorio Institucional EdocUR | spa |
| dc.subject | Gabapentina | spa |
| dc.subject | Pregabalina | spa |
| dc.subject | Lidocaina | spa |
| dc.subject | Costo-efectividad | spa |
| dc.subject | dolor | spa |
| dc.subject.keyword | Gabapentin | eng |
| dc.subject.keyword | Pregabalin | eng |
| dc.subject.keyword | Lidocaine | eng |
| dc.subject.keyword | Cost-effectiveness | eng |
| dc.subject.keyword | pain | eng |
| dc.subject.lemb | Atención médica::Aspectos Económicos | spa |
| dc.subject.lemb | Enfermedades del sistema nervioso::Tratamiento | spa |
| dc.subject.lemb | Gabapentina::Utilización | spa |
| dc.subject.lemb | Lidocaína::Utilización | spa |
| dc.subject.lemb | Pregabalina::Utilización | spa |
| dc.title | Estudio Costo-Efectividad de Lidocaína tópica como adyuvante a Pregabalina y Gabapentina en dolor neuropático periférico en una I.P.S de Bogotá 2011. | spa |
| dc.type | bachelorThesis | eng |
| dc.type.hasVersion | info:eu-repo/semantics/acceptedVersion | |
| dc.type.spa | Trabajo de grado | spa |
