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Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial

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dc.creatorGonzález Ruíz, Katherine
dc.creatorCorrea Bautista, Jorge Enrique
dc.creatorIzquierdo, Mikel
dc.creatorGarcía-Hermoso, Antonio
dc.creatorDominguez-Sanchez, María Andrea
dc.creatorBustos-Cruz, Rosa Helena
dc.creatorGarcía-Prieto, Jorge Cañete
dc.creatorMartínez-Vizcaíno, Vicente
dc.creatorLobelo, Felipe
dc.creatorGonzález-Jiménez, Emilio
dc.creatorPrieto Benavides, Daniel Humberto
dc.creatorTordecilla Sanders, María Alejandra
dc.creatorSchmidt-Riovalle, Jacqueline
dc.creatorPerez, Guillermo
dc.creatorRamírez-Vélez, Robinson
dc.creator.googleGonzález-Ruíz, Katherine
dc.creator.googleCorrea-Bautista, Jorge Enrique
dc.creator.googleIzquierdo, Mikel
dc.creator.googleGarcía-Hermoso, Antonio
dc.creator.googleDominguez-Sanchez, María Andrea
dc.creator.googleBustos-Cruz, Rosa Helena
dc.creator.googleGarcía-Prieto, Jorge Cañete
dc.creator.googleMartínez-Vizcaíno, Vicente
dc.creator.googleLobelo, Felipe
dc.creator.googleGonzález-Jiménez, Emilio
dc.creator.googlePrieto-Benavides, Daniel Humberto
dc.creator.googleTordecilla-Sanders, Alejandra
dc.creator.googleSchmidt-RioValle, Jacqueline
dc.creator.googlePerez, Guillermo
dc.creator.googleRamírez-Vélez, Robinson
dc.date.accessioned2019-09-12T14:39:23Z
dc.date.available2019-09-12T14:39:23Z
dc.date.created2018
dc.date.issued2018
dc.description.abstractBackground: A considerable proportion of contemporary youth have a high risk of obesity-related disorders such as cardiovascular disease, metabolic syndrome, or non-alcoholic fatty liver disease (NAFLD). Although there is consistent evidence for the positive effects of physical activity on several health aspects, most adolescents in Colombia are sedentary. It is, therefore, important to implement strategies that generate changes in lifestyle. The HEPAFIT study aims to examine whether a 6-month exercise program has benefits for hepatic fat content and cardiovascular health outcomes among overweight/obese adolescents from Bogotá, Colombia. Methods/design: Altogether, 100 hundred overweight/obese, sedentary adolescents (aged 11-17 years) attending two public schools in Bogotá, Colombia, will be included in a parallel-group randomized controlled trial. Adolescents will be randomly assigned to an intervention group following one of four curricula: (1) the standard physical education curriculum (60 min per week of physical activity, n = 25) at low-to-moderate intensity; (2) a high-intensity physical education curriculum (HIPE, n = 25), consisting of endurance and resistance games and non-competitive activities, such as running, gymkhanas, lifting, pushing, wrestling, or hauling, for 60-min sessions, three times per week, with an energy expenditure goal of 300 to 500 kcal/session at 75-85% maximum heart rate (HRmax); (3) a low-to-moderate intensity physical education curriculum (LIPE, n = 25) consisting of endurance and resistance games and non-competitive activities (e.g., chasing, sprinting, dribbling, or hopping) for 60-min sessions, three times per week with an energy expenditure goal of 300 kcal/session at 55-75% HRmax; and (4) a combined HIPE and LIPE curriculum (n = 25). The HIPE, LIPE, and combined interventions were performed in addition to the standard physical education curriculum. The primary outcome for effectiveness is liver fat content, as measured by the controlled attenuation parameter 1 week after the end of the intervention program. Discussion: The translational focus may be suitable for collecting new information in a school setting on the possible effects of physical activity interventions to reduce liver fat content and to improve metabolic profiles and the cardiometabolic health of overweight/obese adolescents. This may lead to the more efficient use of school physical education resources. © 2018 The Author(s).eng
dc.format.mimetypeapplication/pdf
dc.identifier.doi10.1186/s13063-018-2721-5
dc.identifier.issn1745-6215
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/20261
dc.language.isoengspa
dc.relation.citationTitleTrials
dc.relation.citationVolumeVol. 19
dc.relation.ispartofTrials, ISSN:1745-6215, Vol. 19 (2018)spa
dc.relation.urihttps://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-018-2721-5spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.bibliographicCitation(2000) Obesity: preventing and managing the global epidemic, , World Health Organizationspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subjectAdolescentspa
dc.subjectAdolescent Obesityspa
dc.subjectCardiovascular Diseasespa
dc.subjectColombiaspa
dc.subjectControlled Studyspa
dc.subjectEndurance Trainingspa
dc.subjectEnergy Expenditurespa
dc.subjectExercisespa
dc.subjectFatty Liverspa
dc.subjectHumanspa
dc.subjectLifting Effortspa
dc.subjectLiver Metabolismspa
dc.subjectParallel Designspa
dc.subjectPhysical Activityspa
dc.subjectPhysical Educationspa
dc.subjectRandomized Controlled Trialspa
dc.subjectRandomized Controlled Trial (Topic)spa
dc.subjectResistance Trainingspa
dc.subjectRunningspa
dc.subjectSingle Blind Procedurespa
dc.subjectWrestlingspa
dc.subjectEnfermedad cardiovascularspa
dc.subjectObesidadspa
dc.subject.ddcEnfermedadesspa
dc.subject.keywordArticlespa
dc.subject.lembEjercicio físicospa
dc.subject.lembTrastornos del metabolismospa
dc.subject.lembObesidadspa
dc.subject.lembHigado grasospa
dc.titleEffects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trialspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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