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Mesenchymal Stromal Cells from Human Wharton's Jelly Modulate the Intraocular Immune Response in a Glucocorticoid Hypertension Model
| dc.creator | Dos Santos Evangelho, K. | spa |
| dc.creator | Cifuentes-González, C. | spa |
| dc.creator | Rojas-Carabali, W. | spa |
| dc.creator | De Vivero-Arciniegas, C. | spa |
| dc.creator | Cañas-Arboleda, M. | spa |
| dc.creator | Salguero, G. | spa |
| dc.creator | Dos Santos Evangelho, K. | spa |
| dc.creator | Cifuentes-González, C. | spa |
| dc.date.accessioned | 2024-07-08T16:55:24Z | |
| dc.date.available | 2024-07-08T16:55:24Z | |
| dc.date.created | 2024-01-01 | spa |
| dc.date.issued | 2024-01-01 | spa |
| dc.description | El glaucoma es una enfermedad neurodegenerativa caracterizada por la pérdida de células ganglionares de la retina. Investigaciones recientes sugieren que cambios inmunológicos, como el desequilibrio de citocinas, pueden afectar su fisiopatología. Esto implica que la inmunomodulación, al igual que la de las células mesenquimales, podría ser una posible vía terapéutica para esta enfermedad. Sin embargo, los efectos de las inyecciones intravítreas de células estromales mesenquimales derivadas de la gelatina de Wharton humana (hWJ-MSC) sobre la respuesta inmune intraocular no se han evaluado en modelos de hipertensión ocular (OH). | spa |
| dc.description.abstract | Glaucoma is a neurodegenerative disease characterized by the loss of retinal ganglion cells. Recent research suggests immunological changes such as cytokine imbalance may affect its pathophysiology. This implies that immunomodulation, like that of mesenchymal cells, could be a potential therapeutic avenue for this disease. However, the effects of intravitreal injections of human Wharton’s jelly-derived mesenchymal stromal cells (hWJ-MSCs) on intraocular immune response have not been assessed in ocular hypertension (OH) models. | eng |
| dc.format.mimetype | application/pdf | spa |
| dc.identifier.doi | https://doi.org/10.1159/000538183 | spa |
| dc.identifier.uri | https://repository.urosario.edu.co/handle/10336/42919 | |
| dc.language.iso | eng | spa |
| dc.relation.ispartof | Ophthalmic Research | spa |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | spa |
| dc.rights.accesRights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.acceso | Abierto (Texto Completo) | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | spa |
| dc.source | Ophthalmic Research | spa |
| dc.source.instname | instname:Universidad del Rosario | spa |
| dc.source.reponame | reponame:Repositorio Institucional EdocUR | spa |
| dc.subject | Glaucoma | spa |
| dc.subject | Células estromales mesenquimales | spa |
| dc.subject | Citoquinas | spa |
| dc.subject | Jalea de Wharton humana | spa |
| dc.subject | Respuesta inmune | spa |
| dc.subject.keyword | Glaucoma | eng |
| dc.subject.keyword | Mesenchymal stromal cells | eng |
| dc.subject.keyword | Cytokine | eng |
| dc.subject.keyword | Human Wharton’s jelly | eng |
| dc.subject.keyword | Immune response | eng |
| dc.title | Mesenchymal Stromal Cells from Human Wharton's Jelly Modulate the Intraocular Immune Response in a Glucocorticoid Hypertension Model | spa |
| dc.type | article | spa |
| dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | spa |
| dc.type.spa | Artículo de Investigación | spa |
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