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Impacto del asma en la severidad de la apnea obstructiva de sueño en niños de 5 a 16 años que viven a gran altura

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dc.contributor.advisorGiraldo Cadavid, Luis Fernando
dc.contributor.otherEscamilla, María Isabel
dc.creatorDuarte Ojeda, Diana Carolina
dc.creatorDueñas, Elida
dc.creator.degreeEspecialista en Epidemiología (en Convenio con el CES)
dc.creator.degreeLevelEspecialización
dc.date.accessioned2025-09-02T12:19:12Z
dc.date.available2025-09-02T12:19:12Z
dc.date.created2025-07-18
dc.date.embargoEndinfo:eu-repo/date/embargoEnd/2027-09-03
dc.descriptionEl asma es una enfermedad respiratoria inflamatoria crónica que se ha relacionado como factor de riesgo para apnea obstructiva del sueño (AOS). No es claro el comportamiento del Polisomnograma (PSG) en niños con asma con y sin AOS. Objetivo. Determinar si el asma se asocia con peores índices de apnea-hipopnea (IAH), apnea obstructiva (IAOH) y de oxigenación en niños residentes a gran altitud. Método. Estudio transversal analítico en niños entre 5 y 16 años residentes en Bogotá, evaluados entre 2019 y 2021. Se analizaron los parámetros del PSG y variables clínicas entre cuatro grupos: AS/ASO (asma con AOS), AOS (AOS sin asma), AS (asma) y grupo control (GC). Resultados. Se incluyeron 294 pacientes (edad media: 9 años; 55,8 % hombres). Distribución por grupos: AS/AOS (40,8 %), AOS (26,5 %), AS (17,0 %), y GC (15,6 %). No se encontró correlación significativa entre la severidad del asma y los índices respiratorios del PSG (rho < 0,1; p > 0,05). Tampoco se observaron diferencias significativas en el IAH (coef. -1,37; IC95%: -3,74 a 0,99), IAOH (coef. 0,15; IC95%: -1,49 a 1,81), ni en otros parámetros respiratorios entre grupos. En el análisis por severidad del asma, no se hallaron diferencias estadísticamente significativas. Sin embargo, un análisis exploratorio del subgrupo con asma grave mostró valores significativamente mayores de IAH, IAOH y ODI en los pacientes con AOS, aunque con tamaño muestral reducido. Conclusiones:. No se identificaron diferencias significativas en la severidad de AOS entre los niños con asma moderada/grave y sin asma. Sin embargo, el hallazgo en el subgrupo con asma grave sugiere una posible interacción entre ambas condiciones en los casos más severos.
dc.format.extent54 pp
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.48713/10336_46387
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/46387
dc.language.isospa
dc.publisherUniversidad del Rosario
dc.publisherUniversidad CES. Facultad de Medicina
dc.publisher.departmentEscuela de Medicina y Ciencias de la Salud
dc.publisher.programMaestría en Epidemiología
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.accesRightsinfo:eu-repo/semantics/embargoedAccess
dc.rights.accesoRestringido (Temporalmente bloqueado)
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
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dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subjectApnea obstructiva del sueño
dc.subjectAlteraciones Respiratorias Durante el Sueño
dc.subjectPolisomnografía
dc.subjectAsma
dc.subjectPediatria
dc.titleImpacto del asma en la severidad de la apnea obstructiva de sueño en niños de 5 a 16 años que viven a gran altura
dc.typebachelorThesis
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de grado
local.department.reportEscuela de Medicina y Ciencias de la Salud
local.regionesBogotá
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