Ítem
Acceso Abierto
Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease
Título de la revista
Autores
Nucci, Marcio
Celis-Ramírez, Adriana Marcela
Gómez Giraldo, Beatríz Lucía
Rojas, Rita
Cornejo-Juárez, Patricia
Riera, Fernando
Vergara, Erika Paola
Cuéllar, Luis E.
Corzo-León, Dora E.
Thompson, Luis
Fecha
2025-02-24
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Editor
Sociedade Brasileira de Infectologia
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Resumen
Abstract
Aspergillosis is a disease caused by the filamentous fungus Aspergillus spp. with a spectrum of clinical presentation that includes invasive and noninvasive forms. The invasive clinical presentation of aspergillosis most frequently affects people with compromised immune systems. In patients with oncohematologic pathology, invasive lung aspergillosis is a significant opportunistic mycosis, because it occurs frequently and has a major impact on morbidity, mortality, and high costs. The global problem of antimicrobial resistance, to which improper use of antifungals contributes, has put Aspergilus spp. in the spotlight, so it is important to generate guidelines for guidance in the proper use of antifungals in the management of invasive lung aspergillosis, to obtain better clinical outcomes and promote rational use of antifungals. This guideline contains recommendations for diagnosing and treating invasive lung aspergillosis in patients with oncohematologic disease, based on evidence and defined through a participatory process of expert consensus, for the Latin American context.
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Keywords
Invasive pulmonary aspergillosis , Hematologic neoplasms
