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Exercise, adipokines and pediatric obesity: A meta-analysis of randomized controlled trials

dc.creatorGarcía-Hermoso, Aspa
dc.creatorCeballos-Ceballos, R J Mspa
dc.creatorPoblete-Aro, C Espa
dc.creatorHackney, A Cspa
dc.creatorMota, Jspa
dc.creatorRamírez-Vélez, Rspa
dc.date.accessioned2020-05-25T23:55:36Z
dc.date.available2020-05-25T23:55:36Z
dc.date.created2017spa
dc.description.abstractBackground/Objective:Adipokines are involved in the etiology of diabetes, insulin resistance, and the development of atherosclerosis and other latent-onset complications. The objective of this meta-analysis was to determine the effectiveness of exercise interventions on adipokines in pediatric obesity.Subjects/Methods:A computerized search was made using three databases. The analysis was restricted to studies that examined the effect of exercise interventions on adipokines (adiponectin, leptin, resistin and visfatin) in pediatric obesity (6-18 years old). Fourteen randomized controlled trials (347 youths) were included. Weighted mean difference (WMD) and 95% confidence intervals were calculated.Results:Exercise was associated with a significant increase in adiponectin (WMD=0.882 ?g ml -1, 95% CI, 0.271-1.493) but did not alter leptin and resistin level. Likewise, exercise intensity and change in body fat; as well as total exercise program duration, duration of the sessions, and change in body fat all significantly influenced the effect of exercise on adiponectin and leptin, respectively.Conclusions:Exercise seems to increase adiponectin levels in childhood obesity. Our results also suggested that exercise on its own, without the concomitant presence of changes in body composition levels, does not affect leptin levels. © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1038/ijo.2016.230
dc.identifier.issn03070565
dc.identifier.issn14765497
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22138
dc.language.isoengspa
dc.publisherNature Publishing Groupspa
dc.relation.citationEndPage482
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage475
dc.relation.citationTitleInternational Journal of Obesity
dc.relation.citationVolumeVol. 41
dc.relation.ispartofInternational Journal of Obesity, ISSN:03070565, 14765497, Vol.41, No.4 (2017); pp. 475-482spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85014041741&doi=10.1038%2fijo.2016.230&partnerID=40&md5=99b9422c06497d4c7355a9d7df2c1ab0spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAdipocytokinespa
dc.subject.keywordhumaneng
dc.subject.keywordLeptinspa
dc.subject.keywordNicotinamide phosphoribosyltransferasespa
dc.subject.keywordResistinspa
dc.subject.keywordAdipocytokinespa
dc.subject.keywordAdiponectinspa
dc.subject.keywordAdipoq proteineng
dc.subject.keywordBibliographic databasespa
dc.subject.keywordBody fatspa
dc.subject.keywordChildhood obesityspa
dc.subject.keywordContent analysisspa
dc.subject.keywordDisease associationspa
dc.subject.keywordDisease controlspa
dc.subject.keywordExercisespa
dc.subject.keywordExercise intensityspa
dc.subject.keywordHumanspa
dc.subject.keywordPhysical activityspa
dc.subject.keywordRandomized controlled trial (topic)spa
dc.subject.keywordReviewspa
dc.subject.keywordSensitivity analysisspa
dc.subject.keywordChildspa
dc.subject.keywordChildhood obesityspa
dc.subject.keywordGlucose blood levelspa
dc.subject.keywordInsulin resistancespa
dc.subject.keywordMeta analysisspa
dc.subject.keywordMetabolismspa
dc.subject.keywordPathophysiologyspa
dc.subject.keywordPhysiologyspa
dc.subject.keywordAdipokinesspa
dc.subject.keywordAdiponectinspa
dc.subject.keywordBlood glucosespa
dc.subject.keywordChildspa
dc.subject.keywordExercisespa
dc.subject.keywordHumansspa
dc.subject.keywordInsulin resistancespa
dc.subject.keywordPediatric obesityspa
dc.subject.keywordRandomized controlled trials as topicspa
dc.titleExercise, adipokines and pediatric obesity: A meta-analysis of randomized controlled trialsspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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