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Psychometric Validation of the M. D. Anderson Symptom Inventory-Head and Neck Module in the Spanish Language

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Sánchez, Daniel
Chala, Andrés
Alvarez, Andrés
Payan, Catalina
Mendoza, Tito
Cleeland, Charles
Sanabria, Alvaro

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2016

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Elsevier Inc.

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Abstract
Context The assessment of cancer-related symptoms requires culturally adapted and psychometrically validated symptom assessment tools. The M. D. Anderson Symptom Inventory-Head and Neck Module (MDASI-HN) is a useful instrument for measuring symptom burden that was specifically developed for head and neck cancer patients. Objectives To validate the Spanish version of the MDASI-HN. Methods We evaluated the psychometric features of the MDASI-HN in patients with head and neck cancer. We evaluated the item-scale correlations and the internal consistency. We conducted principal axis factoring to identify the underlying dimensions as a measure of construct validity. The convergence/concurrent validity was assessed with the University of Washington Quality of Life Questionnaire for Head and Neck Patients, and known-group validity and test-retest reliability also were assessed. Results One hundred thirty patients were included. The mean ± SD age was 60.5 ± 13.6 years; 68% of patients were male, 42% had laryngeal tumors, and 45.9% had Stage III tumors. Forty-seven percent of the patients underwent surgery, 55% underwent radiotherapy, and 36% underwent chemotherapy. The global Cronbach alpha for the HN module was 0.81. The factor analysis identified two factors (Factor 1: speech, mucus, coughing, and constipation; Factor 2: teeth, taste, sores, swallowing, and skin). The correlation with the global score of the University of Washington Quality of Life was -0.68. The difference in the MDASI-HN scores according to Eastern Cooperative Oncology Group performance status was statistically significant (2.72 vs. 4.01, P = 0.006). The intraclass test-retest correlation was 0.62. Conclusion The Spanish version of the MDASI-HN is reliable and valid for evaluating cancer-related symptoms in head and neck cancer patients. © 2016 American Academy of Hospice and Palliative Medicine.
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Adolescent , statistical , Aged , Article , Cancer chemotherapy , Cancer radiotherapy , Cancer staging , Cancer surgery , Clinical assessment tool , Concurrent validity , Constipation , Construct validity , Cronbach alpha coefficient , Distress syndrome , Drowsiness , Dysphagia , Dyspnea , Educational status , Employment status , Fatigue , Female , Gastrostomy , Head and neck cancer , Human , Internal consistency , Larynx tumor , Loss of appetite , M , D , Anderson symptom inventory head and neck module , Major clinical study , Male , Marriage , Nausea , Pain , Psychometry , Quality of life assessment , Rash , Sadness , Skin pain , Sleep disorder , Sore throat , Test retest reliability , Tracheostomy , Validation study , Very elderly , Vomiting , Xerostomia , Clinical trial , Cross-sectional study , Factor analysis , Head and neck tumor , Middle aged , Multicenter study , Pathophysiology , Psychometry , Quality of life , Reproducibility , Severity of illness index , Translating (language) , Young adult , Adolescent , Adult , Aged , Aged, 80 and over , Cross-sectional studies , Factor analysis , Female , Head and neck neoplasms , Humans , Male , Middle aged , Psychometrics , Quality of life , Reproducibility of results , Severity of illness index , Translating , Young adult , Head and neck cancer , Inventory , M , D , Anderson , Quality of life , Symptoms
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